Surface Coating / Alfa Chemistry
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Y-PEG40K-Amine

Basic Information Description Application Features And Benefits
Catalog Number ACMA00039452
Molecular Weight average Mn 40000
Architecture shape : Y-shape
functionality : monofunctional
Quality Level 100
Suitability reactivity: carboxyl reactive
Description Y-shaped PEGs are more selective due to their sterically bulky structure. Compared with the hydroxyl group, the amine group is more reactive to the acylating agent; the reductive amination reaction is easy to occur.
Application Activated PEG derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. PEGylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of PEG improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. In addition to PEGylation, activated PEG derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity.
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