Thiol-poly(ethylene glycol)-b-poly(ε-caprolactone)

Cat.No ACMA00040479

Basic Information Description Application Features And Benefits

Catalog Number	ACMA00040479
Molecular Weight	PCL average Mn 5000 PEG average Mn 5000
Molecular Formula	C5H10S2O[C2H4O]n[C6H10O2]mH
Form	powder or solid
NACRES	NA.23
Quality Level	100
Storage Temperature	−20°C

Description Thiol-poly(ethylene glycol)-b-poly(ε-caprolactone) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PCL block.

Application Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). Additionally, well-defined nanoparticles with tunable size and properties can be prepared by altering the molecular weight ratios between hydrophilic and hydrophobic blocks, as well as by controlling formulation parameters. The thiol functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.

Features And Benefits These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media.

Our products and services are for research use only and cannot be used for any clinical purpose.

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