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Pyridyl disulfide-poly(ethylene glycol)-b-poly(ε-caprolactone)

Pyridyl disulfide-poly(ethylene glycol)-b-poly(ε-caprolactone)

Cat.No ACMA00040478

Basic Information Description Application Features And Benefits

Catalog Number	ACMA00040478
Synonyms	PDS-PEG-PCL, PEG-PCL, PEG-b-PCL
Molecular Weight	PCL average Mn 5000 PEG average Mn 5000
Molecular Formula	C10H14NOS3[C2H4O]n[C6H10O2]mH
Form	powder or solid
Quality Level	100
Storage Temperature	−20°C

Description Pyridyl disulfide-poly(ethylene glycol)-b-poly(ε-caprolactone) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PCL block.

Application Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). Additionally, well-defined nanoparticles with tunable size and properties can be prepared by altering the molecular weight ratios between hydrophilic and hydrophobic blocks, as well as by controlling formulation parameters. The PDS functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.

Features And Benefits These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media.