Polyester bis-MPA dendron, carboxyl, 1 NHBoc (core), generation 1
Basic Information
Description
Application
Features And Benefits
Description |
Bis-MPA (or 2,2-Bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers. |
Application |
Dendrons synthesized from bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research s. These materials have been used in many s such as signal amplification in bioassays and in drug delivery s. Both the carboxylic acid-functionalized dendrimers and amine-functionalized (after Boc deprotection) core can be readily used in EDC or DCC coupling reactions with amine or carbonyl-containing compounds, respectively, to yield highly functionalized materials for a variety of biomedical s. |
Features And Benefits |
Polymer architecture: Dendron Generation: 1 Core functional group: Boc-protected amine End Group Functionality: Carboxylic acid No. Surface Groups: 2 Calculated Mol. Wt.: 681.69 g/mol Boc: tert-Butyloxycarbonyl bis-MPA : 2,2-Bis(hydroxymethyl)propionic acid |