Polyester bis-MPA dendron, acetylene, 1 NHBoc (core), generation 2
Basic Information
Description
Application
Features And Benefits
| Description |
Bis-MPA (or 2,2-Bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers. |
| Application |
Dendrons synthesized from Bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research s. These materials have been used in many s such as signal amplification in bioassays and in drug delivery s. These alkyne-functionalized dendrimers can be readily functionalized using either copper(I)-catalysed alkyne-azide cycloaddition (CuAAC), strain-promoted alkyne-azide cycloaddition (SPAAC), or thiol-yne click reactions. Additionally, the amine-functionalized core can be readily used in EDC or DCC coupling reactions (after Boc deprotection) with carbonyl-containing compounds to yield highly functionalized materials for a variety of biomedical s. |
| Features And Benefits |
Polymer architecture: Dendron
Generation: 2
Core functional group: Boc-protected amine
End Group Functionality: Alkyne
No. Surface Groups: 4
Calculated Mol. Wt.: 1266.26 g/mol
Boc : tert-Butyloxycarbonyl
Bis-MPA : 2,2-Bis(hydroxymethyl)propionic acid |
