Polyester bis-MPA dendron 4 NHBoc, 1 thiol (core)

Cat.No ACMA00040552

Basic Information Description Application Features And Benefits

Catalog Number	ACMA00040552
Synonyms	Bis-MPA dendron, PFd-G2-Thiol-NH-BOC
Molecular Weight	1111.25
Form	solid
NACRES	NA.23
Quality Level	100
Storage Temperature	−20°C

Description Bis-MPA (or 2,2-Bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers.

Application Dendrons synthesized from bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research s. These materials have been used in many s such as signal amplification in bioassays and in drug delivery s. After Boc deprotection, amine-functionalized dendrons can be readily used in EDC or DCC coupling reactions with carbonyl-containing compounds to yield highly functionalized materials for a variety of biomedical s. Additionally, the thiol-core can be readily conjugated via a thiol-ene click reaction, Michael addition reactions, or disulfide exchange.

Features And Benefits Polymer architecture: Dendron
End Group Functionality: Boc-protected amine
Boc: tert-Butyloxycarbonyl
Bis-MPA : 2,2-Bis(hydroxymethyl)propionic acid.

Our products and services are for research use only and cannot be used for any clinical purpose.

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