Surface Coating / Alfa Chemistry

Polyester bis-MPA dendron

Cat.No ACMA00015872

Basic Information Description Application Features And Benefits
Catalog Number ACMA00015872
Synonyms Bis-MPA dendron, PFd-G4-BocNH-acetylene
Molecular Weight 4317.08
Form solid
Quality Level 100
Storage Temperature −20°C
Description Bis-MPA (or 2,2-Bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers.
Application Dendrons synthesized from bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research s. These materials have been used in many s such as signal amplification in bioassays and in drug delivery s. These alkyne-functionalized dendrimers can be readily functionalized using either copper(I)-catalysed alkyne-azide cycloaddition (CuAAC), strain-promoted alkyne-azide cycloaddition (SPAAC), or thiol-yne click reactions. Additionally, the amine-functionalized core can be readily used in EDC or DCC coupling reactions (after Boc deprotection) with carbonyl-containing compounds to yield highly functionalized materials for a variety of biomedical s.
Features And Benefits Polymer architecture: Dendron
Generation: 4
Core functional group: Boc-protected amine
End group functionality: Alkyne
No. surface groups: 16
Calculated mol. wt.: 4317.12 g/mol
Boc: tert-Butyloxycarbonyl
Bis-MPA: 2,2-Bis(hydroxymethyl)propionic acid

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