Polyester bis-MPA dendron 2 NHBoc, 1 acetylene (core)
Basic Information
Description
Application
Features And Benefits
Description |
Bis-MPA (or 2,2-Bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers. |
Application |
Dendrons synthesized from bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research s. These materials have been used in many s such as signal amplification in bioassays and in drug delivery s. After Boc deprotection, amine-functionalized dendrons can be readily used in EDC or DCC coupling reactions with carbonyl-containing compounds to yield highly functionalized materials for a variety of biomedical s. Additionally, the alkyne-core can be readily conjugates using either copper(I)-catalyzed alkyne-azide cycloaddition (CuAAC) or strain-promoted alkyne-azide cycloaddition (SPAAC). |
Features And Benefits |
Polymer architecture: Dendron End Group Functionality: Boc-protected amine Boc : tert-Butyloxycarbonyl Bis-MPA : 2,2-Bis(hydroxymethyl)propionic acid |