Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co-glycolide)

Basic Information Description Application Features And Benefits

Catalog Number	ACMA00040483
Synonyms	PLGA-PEG-PLGA
Molecular Weight	PEG average Mn 1,500 (by NMR) PLGA average Mn 3,200 (by NMR) average Mn (1,600-1,500-1,600)
Molecular Formula	H((C3H4O2)x(C2H2O2)y)m((C2H4O)z)nO((C3H4O2)x(C2H2O2)y)mH
Form	semisolid
Quality Level	100
Storage Temperature	−20°C

Description PLGA-PEG-PLGA is an amphiphilic triblock copolymer which can self-assemble into micelles in aqueous medium due to the hydrophobic interactions present in the hydrophobic segments.

Application The PEG segment imparts hydrophilicity and improves the biocompatibility of the copolymer. The PLGA segment forms a hydrophobic core and can solubilize hydrophobic drugs. These copolymers are widely used as nanocarriers for the sustained release of drugs. Also this polymer exhibits thermogelation behavior. When applied in biomedical applications, the temperature responsive nature of the copolymer can be tuned to induce an in situ gelation at physiological temperature to provide controlled drug release. These materials have been explored for biomedical applications as temperature-responsive biodegradable systems for drug delivery, tissue engineering and wound healing.

Features And Benefits Good biocompatibility;
Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.

Our products and services are for research use only and cannot be used for any clinical purpose.

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