Poly(L-lactide-co-glycolide)

Basic Information Description Application Features And Benefits

Catalog Number	ACMA00040432
Synonyms	PLGA
Molecular Formula	(C4H4O4)m(C6H8O4)n
Form	chips
Quality Level	100
Storage Temperature	−20°C

Description Poly(L-lactide-co-glycolide) (PLGA) is a biodegradable and biocompatible copolymer synthesized from the ring opening polymerization of lactide and glycolide. Due to the ester linkages found in the polymer backbone, these polymers are able to degrade via hydrolysis. Depending on the ratio of monomers used and polymer block structure, different forms of PLGA can be obtained. These differing forms yield materials with different degrees of crystallinity, thermal transitions, solubility, and rates of degradation.

Application Poly(L-lactide-co-glycolide) (PLGA) is a biodegradable and biocompatible copolymer for use in biomedical research devices, such as grafts, sutures, implants, prosthetic devices, surgical sealant films, scaffolds for tissue engineering applications, micro and nanoparticles. PLGA is also utilized in drug delivery research, such as in the synthesis and application of polymer-drug conjugates.

Features And Benefits Non-toxic, biodegradable in soil, broad miscibility, mechanical compatibility with many polymers and good adhesion to a broad spectrum of substrates.