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Poly(ethylene glycol) methyl ether maleimide

Basic Information Description Application Features And Benefits
Catalog Number ACMA00014043
Synonyms Methoxy PEG maleimide, PEG methyl ether maleimide
Molecular Weight average Mn 2000
Melting Point 48-52 °C
Architecture shape: linear
functionality: monofunctional
Form solid
NACRES NA.23
Packaging Packaging
1, 5 g in glass bottle
Quality Level 100
αEnd methoxy
ΩEnd maleimide
Description Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation.
Application Poly(ethylene glycol) methyl ether maleimide is a maleimide-functionalized poly(ethylene glycol). Due to the maleimide-functionalization, this material can be used to rapidly conjugate thiol-containing biomolecules, APIs, or targeting ligands.
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