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Poly(ethylene glycol) methyl ether-block-poly(L-lactide-co-glycolide)

Poly(ethylene glycol) methyl ether-block-poly(L-lactide-co-glycolide)

Basic Information Description Application Features And Benefits

Catalog Number	ACMA00014050
Synonyms	PEG-PLGA, PEG-b-PLGA
Molecular Weight	PEG average Mn 5,000 PLGA average Mn 25,000
Molecular Formula	CH3[C2H4O]nO[(C2H2O2)x(C3H4O2)y]mH
Composition	lactide:glycolide 50:50
Form	powder
NACRES	NA.23
Packaging	1 g in glass bottle
Quality Level	100
Storage Temperature	2-8°C

Description Poly(L-lactide-co-glycolide) (PLGA) is a biodegradable and biocompatible copolymer for use in biomedical research devices, such as grafts, sutures, implants.

Application Amphiphilic block copolymers (AmBC) are made up of two chemically different homopolymer blocks. One of the block is hydrophilic and the other one is hydrophobic. These macromolecules have the properties to self-assemble when dissolved in an aqueous media. PEG-PLGA is one the most commonly used biodegradable amphiphilic block copolymers for drug delivery applications. PEG is the hydrophilic part and PLGA is the hydrophobic part.Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs

Features And Benefits Good biocompatibility, low immunogenicity and good degradability.
Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.