Surface Coating / Alfa Chemistry

Poly(ethylene glycol) linear dendrimer, NHBoc terminated, PEG Mn 6000, generation 3

Basic Information Description Application Features And Benefits
Catalog Number ACMA00040518
Synonyms PFD-G3-PEG6k-NHBOC, Dendron bifunctionalized PEG
Molecular Weight 10373.88
Form solid
Quality Level 100
Storage Temperature −20°C
Description Bis-MPA (or 2,2-Bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers.
Application Dendrons synthesized from Bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research s. These materials have been used in many s such as signal amplification in bioassays and in drug delivery s. PEG-core dendrimers feature excellent solubility in water and a high degree of functionality per PEG chain, making them strong candidates for advanced drug delivery systems or as targeting vessels. Additionally, the terminal amine groups can readily be used in EDC or DCC coupling reactions (after Boc deprotection) with carbonyl-containing compounds, to yield highly functionalized materials for a variety of biomedical s.
Features And Benefits Polymer architecture: Dendron-functionalized PEG
Generation: 3
PEG Average Mn: 6,000
End Group Functionality: Boc-protected amine
No. Surface Groups: 16
Calculated Mol. Wt.: 10373.98 g/mol
Boc: tert-Butyloxycarbonyl
Bis-MPA: 2,2-Bis(hydroxymethyl)propionic acid

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