Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) dimethacrylate, average Mn ~12500

Cat.No ACMA00040507

Basic Information Description Application Features And Benefits

Catalog Number	ACMA00040507
Synonyms	Pluronic Dimethacrylate, Pluronic F-127 dimethacrylate, PEG-PPG-PEG
Molecular Weight	average Mn ~12,500
Molecular Formula	C4H5O[C2H4O]x[C3H6O]y[C2H4O]zC4H5O2
Form	powder
Quality Level	100
Storage Temperature	−20°C

Description Poloxamers are nonionic, triblock copolymers containg a central hydrophobic chain of poly(propylene glycol) (PPG) and two terminal hydrophilic chains of poly(ethylene glycol) (PEG).

Application Due to their amphiphilic structure, poloxamer solutions feature temperature dependent self-assembling and thermo-gelling behavior. Concentrated aqueous solutions of poloxamers are liquid at low temperature and form a gel at higher temperature, in a reversible process. This characteristic has allowed for these materials to be used as drug carriers for most routes of administration including oral, topical, intranasal, ocular, and parenteral. Methacrylate-modified derivatives are most commonly used as thermosensitive hydrogels for drug delivery and 3D bioprinting applications. After casting or printing, the material can be crosslinked to preserve the hydrogel structure.

Features And Benefits Good biocompatibility;
Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.

Our products and services are for research use only and cannot be used for any clinical purpose.

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