Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) dimethacrylate

Cat.No ACMA00040506

Basic Information Description Application Features And Benefits

Catalog Number	ACMA00040506
Synonyms	F-108 dimethacrylate, PEG-PPG-PEG, Pluronic dimethacrylate
Molecular Weight	average Mn ~14,600
Molecular Formula	C4H5O[C2H4O]x[C3H6O]y[C2H4O]zC4H5O2
Contains	≤1500 ppm MeHQ
Form	powder
Quality Level	100
Storage Temperature	−20°C

Description Poloxamers are nonionic, triblock copolymers containg a central hydrophobic chain of poly(propylene glycol) (PPG) and two terminal hydrophilic chains of poly(ethylene glycol) (PEG).

Application This characteristic has allowed for these materials to be used as drug carriers for most routes of administration including oral, topical, intranasal, ocular, and parenteral. Methacrylate-modified derivatives are most commonly used as thermosensitive hydrogels for drug delivery and 3D bioprinting applications. After casting or printing, the material can be crosslinked to preserve the hydrogel structure.

Features And Benefits Due to their amphiphilic structure, poloxamer solutions feature temperature dependent self-assembling and thermo-gelling behavior. Concentrated aqueous solutions of poloxamers are liquid at low temperature and form a gel at higher temperature, in a reversible process.

Our products and services are for research use only and cannot be used for any clinical purpose.

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