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Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) diacrylate, average Mn ~12500

Basic Information Description Application Features And Benefits
Catalog Number ACMA00040503
Synonyms Poloxamer F127 diacrylate, PEG-PPG-PEG
Molecular Weight average Mn ~12,500
Molecular Formula C3H3O[C2H4O]x[C3H6O]y[C2H4O]zC3H3O2
Form powder
Quality Level 100
Storage Temperature −20°C
Description PEG-PPG-PEG symmetric triblock copolymer constitutes of poly(ethylene oxide)(PEO) and poly (propylene oxide) (PPO). The unique characteristic of PPO block exhibiting hydrophobicity at temperatures above 288K and solubility in water at temperatures below 288K lead to formation of micelle consisting of PEO-PPO-PEO triblock copolymers. Some studies report that the hydrophobic core contains PPO block and a hydrophilic corona is comprised of PEO block. In 30wt% aqueous solution PEG-PPG-PEG forms a cubic gel phase.
Application Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) diacrylate (PEG-PPG-PEG) is a bifunctional acrylate-based amphiphilic triblock copolymer, which can be used in applications such as pharmaceutics, biomedical and personal care products. It can also be used in the synthesis of alternating block polyurethanes, which can be potentially used in drug delivery.
Features And Benefits Good biocompatibility;
Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.

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