Poly(D,L-lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(D,L-lactide-co-glycolide) based poly(ether ester urethane), average Mn 6000-12000

Cat.No ACMA00040481

Basic Information Description Application Features And Benefits

Catalog Number	ACMA00040481
Synonyms	Poly(D,L-lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(D,L-lactide-co-glycolide) based poly(ether ester urethane)
Molecular Weight	PEG average Mn 400 average Mn 6,000-12,000
Molecular Formula	[C2H2N2O2R[(C3H4O2)x(C2H2O2)y]m[C2H4O]lO[(C3H4O2)x(C2H2O2)y]m]n
Canonical SMILES	CC(N[R]NC(OC(C)C(OCC(OCCOC(C(C)OC(COC)=O)=O)=O)=O)=O)=O.CC(N[R]NC(OCCCOC)=O)=O
Packaging	1, 5 g in glass bottle
Quality Level	100
Storage Temperature	2-8°C

Description The polymers are bioresorbable aliphatic polyesters comprised of a range of different ratios of lactide and glycolide monomers, PLA stereochemistries, and end-group functionalization. These biodegradeable homopolymers and copolymers of lactide and glycolide afford a variety of properties that range from very stiff, hard semi-crystalline materials with long degradation times, to softer, amorphous materials with faster degradation rates.

Application This poly(ether ester urethane) based on PLGA-PEG-PLGA triblock copolymers linked with a diisocyanate is a biodegradable; resorbable gel former for use in drug delivery systems.

Features And Benefits This polymer doesn't rely on temperature or pH to induce gelation and therefore form more consistent and faster-setting drug delivery depots.
Through combination of various gel formers and/or diluents; drug release profiles may be modulated to exhibit fast burst release through extended (up to 1 month) zero-order release profile.

Our products and services are for research use only and cannot be used for any clinical purpose.

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