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Poly(D,L-lactide-co-glycolide)(50:50)-b-poly(ethylene glycol)

Poly(D,L-lactide-co-glycolide)(50:50)-b-poly(ethylene glycol)

Basic Information Description Application Features And Benefits

Catalog Number	ACMA00040489
Synonyms	PLGA-b-PEG, PLGA-PEG
Molecular Formula	H[(C3H4O2)x(C2H2O2)y]mO[C2H4O]nCH3
Quality Level	100
Storage Temperature	2-8°C

Description The polymers are bioresorbable aliphatic polyesters comprised of a range of different ratios of lactide and glycolide monomers, PLA stereochemistries, and end-group functionalization. These biodegradeable homopolymers and copolymers of lactide and glycolide afford a variety of properties that range from very stiff, hard semi-crystalline materials with long degradation times, to softer, amorphous materials with faster degradation rates.

Application Biocompatible, amphiphilic block copolymer composed of a hydrophilic PEG block and a hydrophobic poly(D,L-lactide-co-glycolide) (PLGA) block. These materials have been used in control release and nanoparticle formulation for drug encapsulation and delivery applications. Well-defined materials with varying properties can be prepared by controlling the relative length of each polymer block. Hydroxyl termination allows for facile further chemical modification of these materials.

Features And Benefits Good biocompatibility;
Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.