N-Hydroxysuccinimide ester-poly(ethylene glycol)-b-poly(D,L lactide)

Basic Information Description Application Features And Benefits

Catalog Number	ACMA00040454
Synonyms	NHS ester PEG-PLA, NHS-PEG-PLA, NHS ester PEG-PDLA, NHS-PEG-PDLA
Molecular Weight	PDLA average Mn 16,000 (by NMR) PEG average Mn 5,000 (by NMR)
Molecular Formula	HO(C3H4O2)m(C2H4O)nC7H8NO4
Form	powder or chunks
Quality Level	100
Storage Temperature	−20°C

Description N-Hydroxysuccinimide ester-poly(ethylene glycol)-b-poly(D,L lactide) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLA block. T

Application These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). The NHS functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.

Features And Benefits Good biocompatibility;
Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.

Our products and services are for research use only and cannot be used for any clinical purpose.

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