mPEG20K-Vinyl sulfone

Basic Information Description Application Features And Benefits

Catalog Number	ACMA00039436
Purity	≥ 95% (1H-NMR). Product conforms to structure by 1H-NMR.
Form	solid
Quality Level	100
Storage Temperature	Store between 0 and -5 °C. Avoid exposure to light. Ensure the vial lid is sealed when not in use.

Description mPEG-VS is a linear monofunctional PEG reagent with a thiol-reactive vinylsulfone group. VS selectively reacts with free thiols, SH, sulfhydryl or sulfhydryl groups for site-specific PEGylation of peptides and proteins.

Application Activated PEG derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. PEGylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of PEG improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. In addition to PEGylation, activated PEG derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity.

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