Surface Coating / Alfa Chemistry

Hexaethylene glycol

Cat.No ACM2615158-1

Basic Information Description Application Features And Benefits
CAS 2615-15-8
Catalog Number ACM2615158-1
Synonyms 3,6,9,12,15-Pentaoxaheptadecane-1,17-diol
IUPAC Name 2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Molecular Weight 282.33
Molecular Formula C12H26O7
InChI InChI=1S/C12H26O7/c13-1-3-15-5-7-17-9-11-19-12-10-18-8-6-16-4-2-14/h13-14H,1-12H2
Boiling Point 217 °C at 4 mmHg (lit.)
Melting Point 5-7° C (lit.)
Purity ≥96%
Density 1.127 g/mL at 25 °C
Appearance Liquid
Assay 97%
Beilstein REAXYS Number 1638281
EC Number 220-045-1
MDL Number MFCD00002877
Packaging Packaging
5, 25 g in poly bottle
PubChem ID 24855697
Quality Level 200
Refractive Index n20/D 1.465 (lit.)
αEnd hydroxyl
ΩEnd hydroxyl
Description Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation.
Application Activated PEG derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. PEGylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of PEG improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. In addition to PEGylation, activated PEG derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity.
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