Surface Coating / Alfa Chemistry


Basic Information Description Application Features And Benefits
Catalog Number ACMA00039397
Purity ≥ 95%
Quality Level 100
Storage Temperature Store between 0 and -5 °C. Avoid exposure to light. Ensure the vial lid is sealed when not in use.
Description High quality Fmoc amine PEG succinimidyl carboxymethyl ester, standard quality specification with >90% degree of substitution.
Application Activated PEG derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. PEGylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of PEG improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. In addition to PEGylation, activated PEG derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity.
Features And Benefits Heterobifunctional Fmoc amine PEG succinimidyl carboxymethyl ester products with FMOC protected amines are commonly used as crosslinkers or spacers between two different chemical entities. The PEG moiety in the heterofunctional PEG derivatives provides water solubility, biocompatibility and flexibility. Applications are particularly suitable for the development of antibody drug conjugates (ADCs)

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