Carboxylic acid-poly(ethylene glycol)-b-poly(D,L lactide)

Basic Information Description Application Features And Benefits

Catalog Number	ACMA00040442
Synonyms	Carboxylic acid PEG-PDLA, COOH-PEG-PLA, Carboxylic acid-PEG-PLA, COOH-PEG-PDLA
Molecular Weight	PDLA average Mn 55,000 (by NMR) PEG average Mn 5,000 (by NMR)
Molecular Formula	HO(C3H4O2)m(C2H4O)nC2H3O2
Form	powder or chunks
Quality Level	100
Storage Temperature	−20°C

Description Carboxylic acid-poly(ethylene glycol)-b-poly(D,L lactide) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLA block.

Application Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). The carboxylic acid functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.

Features And Benefits These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media.

Our products and services are for research use only and cannot be used for any clinical purpose.

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