Home
Products
Biomedical Polymers
Block Copolymers
Diblock Copolymers
Carboxylic acid-poly(ethylene glycol)-b-poly(ε-caprolactone)

Carboxylic acid-poly(ethylene glycol)-b-poly(ε-caprolactone)

Cat.No ACMA00040443

Basic Information Description Application Features And Benefits

Catalog Number	ACMA00040443
Synonyms	Carboxylic acid-PEG-PCL, PEG-PCL, PEG-b-PCL, Carboxylic acid PEG-PCL diblock copolymer
Molecular Weight	PCL average Mn 5000 PEG average Mn 5000
Molecular Formula	C6H11O3S[C2H4O]n[C6H10O2]mH
Form	powder or solid
NACRES	NA.23
Quality Level	100
Storage Temperature	−20°C

Description Carboxylic acid-poly(ethylene glycol)-b-poly(ε-caprolactone) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PCL block.

Application These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). Additionally, well-defined nanoparticles with tunable size and properties can be prepared by altering the molecular weight ratios between hydrophilic and hydrophobic blocks, as well as by controlling formulation parameters. The carboxylic acid functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.

Features And Benefits Good biocompatibility;
Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.