Fixed or removable dentures are frequently supported with dental implants to replace missing teeth. Biocompatible dental implants have always been the main choice to improve the therapeutic impact as medical technology has progressed. Alfa Chemistry is a leader in the field of medical surface coatings, having created a wide range of antibacterial, bioactive, and therapeutic surface modifications and coatings for dental implants. Please contact us if you'd like to learn more about dental implant treatment coatings.
Therapeutic Implant Coatings
Dental implant coatings are necessary to improve tissue-biomaterial interactions and boost osseointegration, in addition to high biocompatibility. The production of biocompatible nanomaterials to efficiently manage the processes of tissue regeneration, cell adhesion, proliferation, and differentiation is one of the current biomimetic approaches to dental implant coatings. Alfa Chemistry has investigated several organic and inorganic nanocoating agents, including graphene, proteins, and peptides. With these surface treatments and coatings, we can immobilize bioactive compounds, osteoconductive medicines, and growth factors on implant coatings, potentially improving treatment outcomes. The following are some of the therapeutic implant coatings that we can provide.
Biomimetic and Bioactive Coatings
Alfa Chemistry deposited a biomimetic layer of calcium phosphate (CaP) and hydroxyapatite (HA) coatings on dental implants to improve osteoconductivity and osseointegration. These coatings are currently used to achieve biocompatibility and are one of the most successful clinical treatment coatings for dental implants to enhance peri-implant bone formation. We used innovative physical deposition and chemical procedures to manufacture 100 nm thin CaP/HA coatings, and organic implant nanocoatings containing proteins, polysaccharides, and medicines were integrated into the CaP and HA lattices to enable Has a variety of therapeutic characteristics.
Antibacterial Coatings
Dental implant infections are frequently complex, multivariate, and difficult to treat. By developing a physically protective biofilm, implant surfaces provide a substrate for bacterial adherence and restrict systemic antibiotic diffusion, resulting in relatively limited medication availability at the infection site. Alfa Chemistry is always working to improve and create antibiotic therapeutic coatings for dental implants in order to cure persistent peri-implant infections. For local implant-bone infections, we have presented different implant coating therapies.
Fig 1. Drug release from implantable biomaterials and description of various types of carrier-based drug-releasing biomaterials. (Zafar M. S, et al. 2020)
To prevent infection at the implant site, we wrap dental implants with a bioactive coating of antibiotics (gentamicin, amoxicillin, and vancomycin). Experiments have revealed that covering a polylactic acid implant with 10% gentamicin lowers implant-related infections considerably.
Chlorhexidine (CHX) is a broad-spectrum organic antibacterial and antifungal drug commonly used to treat periodontal infections. During the early stages of implant placement, our buildable CHX-polybenzyl acrylate titanium implant coating is especially effective for controlling bacterial infections surrounding dental implants.
Reference
- Zafar M. S, et al. (2020). "Customized Therapeutic Surface Coatings for Dental Implants." Coatings. 10: 568.
